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Nadine Traulsen Beschleunigtes Magnetic Particle Imaging


Das bildgebende Verfahren Magnetic Particle Imaging (MPI) ist in der Lage, die räumliche Verteilung eines magnetischen Tracers mit hoher räumlicher und zeitlicher Auflösung darzustellen. Dabei können diese beiden Parameter klassischerweise nicht unabhängig voneinander gesteigert werden, stattdessen bedingt eine Erhöhung der zeitlichen Auflösung eine Verringerung der räumlichen Auflösung. Im vorliegenden Werk wird Compressed Sensing (CS) zur Abtastung und Rekonstruktion des MPI-Signals eingesetzt, um die Signalaufnahme zu beschleunigen und damit die zeitliche Auflösung zu erhöhen. Dieses Verfahren ermöglicht eine verlustfreie Rekonstruktion des Bildes mit gleichbleibender räumlicher Auflösung. Die erzielte Beschleunigung resultiert dabei aus der Aufnahme eines unterabgetasteten Messsignals mit wesentlich weniger Abtastwerten als durch das Nyquist-Shannon-Abtasttheorem vorgegeben.

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7th International Workshop on Magnetic Particle Imaging (IWMPI 2017)


Magnetic Particle Imaging (MPI) is a novel imaging modality that uses various static and oscillating magnetic fields to image the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs) with high sensitivity, no tissue background, and no ionizing radiation. The method exploits the non-linear magnetization behavior of the SPIOs, and has shown great potential to surpass current in vivo imaging modalities in terms of sensitivity, safety, quantitation, and spatio-temporal resolution. MPI is well suited for clinical applications such as angiography, cancer imaging, and inflammation imaging; as well as research applications such as stem cell imaging and small animal imaging.

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6th International Workshop on Magnetic Particle Imaging (IWMPI 2016)


Magnetic Particle Imaging (MPI) is a novel imaging modality that uses various static and oscillating magnetic fields to image the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs) with high sensitivity, no tissue background, and no ionizing radiation. The method exploits the non-linear magnetization behavior of the SPIOs, and has shown great potential to surpass current in vivo imaging modalities in terms of sensitivity, safety, quantitation, and spatio-temporal resolution. MPI is well suited for clinical applications such as angiography, cancer imaging, and inflammation imaging; as well as research applications such as stem cell imaging and small animal imaging.

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Klaas Bente Implementation of a Magnetic Particle Imaging System for Dynamic Field Free Line


A new tomographic imaging modality called magnetic particle imaging (MPI) has been proposed in 2005. Using the non-linear magnetization curve of specific nanoparticles, a detectable signal proportional to the concentration of these particles can be generated. For medical imaging the tracer material can be injected into the blood system. Due to fast image acquisition, not only morphological, but also functional imaging is possible. The feasibility of medical imaging with this technique could be demonstrated at real time imaging of a beating mouse heart. Spatial encoding is provided by superimposing dedicated external magnetic fields. For the resulting shape of this field a field free line has been proposed. This work presents the implementation of the MPI system with a discretely rotatable and dynamically translatable field free line.

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Matthias Weber Optimierung der Permanentmagnetengeometrie zur Generierung eines Selektionsfeldes fur Magnetic Particle Imaging


Magnetic-Particle-Imaging (MPI) ist ein neues bildgebendes Verfahren, das es ermöglicht, die Verteilung superparamagnetischer Nanopartikel in hoher zeitlicher und örtlicher Auflösung zu bestimmen. Das Auflösungsvermögen des Systems hängt dabei direkt von dem für die Ortskodierung genutzten Selektionsfeld ab. Kürzlich wurde ein MPI-Scanner vorgestellt, der dieses Selektionsfeld mit Permanentmagneten generiert. Ausgehend von dieser Anordnung werden in diesem Werk die Geometrie- und Magnetisierungsparameter der Permanentmagneten optimiert. Durch die erreichte Erhöhung der Gradientenstärke um 39 %, kann die Auflösung von Magnetic-Particle-Imaging deutlich gesteigert werden, ohne das Messsystem zu vergrößern. Alternativ ist es möglich, das Permanentmagnetvolumen um 44 % zu minimieren, ohne dabei den Ausgangsgradienten zu ändern.

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Xiaoyuan Chen Nanoplatform-Based Molecular Imaging


The cutting-edge guide on advancing the science of molecular imaging using nanoparticles Nanoplathform-Based Molecular Imaging provides rationale for using nanoparticle-based probes for molecular imaging, then discusses general strategies for this underutilized, yet promising, technology. It addresses general strategies of particle synthesis and surface chemistry, applications in computed tomography optical imaging, magnetic resonance imaging, ultrasound, multimodality imaging, theranostics, and finally, the clinical perspectives of nanoimaging. This comprehensive volume summarizes the opinions of those in the forefront of research and describes the latest developments by emphasizing fundamentals and initiating hands-on application.

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4th International Workshop on Magnetic Particle Imaging


Magnetic Particle Imaging (MPI) is a novel imaging modality that uses various static and oscillating magnetic fields to image the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs) with high sensitivity, no tissue background, and no ionizing radiation. The method exploits the non-linear magnetization behavior of the SPIOs, and has shown great potential to surpass current in vivo imaging modalities in terms of sensitivity, safety, quantitation, and spatio-temporal resolution. MPI is well suited for clinical applications such as angiography, cancer imaging, and inflammation imaging; as well as research applications such as stem cell imaging and small animal imaging. Since the first workshop in 2010, the International Workshop on MPI (IWMPI) has been the premier forum for researchers working in the MPI field. The workshop aims at covering the status and recent developments of both the instrumentation and the tracer material, as they are equally important in designing a well performing MPI system. The main topics presented at the workshop include hardware developments, image reconstruction and systems theory, nanoparticle physics and theory, nanoparticle synthesis, spectroscopy, patient safety, and medical/research applications of MPI.

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Matthias Weber Power-Loss Optimized Field-Free Line Generation for Magnetic Particle Imaging


Magnetic Particle Imaging (MPI) is a novel medical imaging technology that is able to acquire the distribution of superparamagnetic iron oxide nanoparticles in real-time with high spatial and temporal resolution. Spatial encoding is realized by a magnetic field configuration generating a field-free point (FFP). Therefore, the FFP is moved through the field of view (FOV). However, at low particle concentrations the signal-to-noise ratio (SNR) decreases and therefore image quality worsens. An enhanced encoding scheme uses instead of the FFP the concept of a field-free line (FFL), whereby a gain of sensitivity of one order of magnitude can be realized. Simulation studies approximate power consumption to a minimum and improve field homogeneity with the result that fast Radon-based reconstruction techniques are feasible. On the basis of these studies, this book describes the manufacturing of an optimized scanner topology realizing an excellent field quality with the help of customized curved rectangular coils. Furthermore, the power loss is efficiently minimized.

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Mandy Ahlborg Bildgebungskonzepte fur Magnetic Particle Imaging


Dieses Buch beschäftigt sich mit verschiedenen Bildgebungskonzepten und Rekonstruktionsansätzen für große Bildgebungsvolumen bei Verwendung des Magnetic Particle Imaging (MPI). MPI ist ein neues und innovatives medizinisches Bildgebungsverfahren, das die Visualisierung magnetischer Nanopartikel erlaubt. Werden solche Partikel in den menschlichen Organismus eingebracht, können diese mit Hilfe von den bei MPI verwendeten Magnetfeldern sichtbar gemacht werden. So entsteht eine Vielzahl an zukunftsweisenden diagnostischen Möglichkeiten.Die technische Realisierung eines MPI-Gerätes sowie medizinische Sicherheitsaspekte limitieren jedoch die inhärente Größe des Bildgebungsvolumens. In diesem Buch werden aktuelle Forschungsergebnisse vorgestellt, die eine Vergrößerung des Volumens in den gegebenen Rahmenbedingungen ermöglichen und gleichzeitig eine schnelle und somit effektive Bildrekonstruktion für eine klinische Perspektive liefern. Die entstandenen Methoden stellen dabei wichtige Meilensteine für die Weiterentwicklung der Bildgebung mit MPI dar.

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Anselm von Gladiß Compressed Sensing und Sparse Rekonstruktion bei Magnetic Particle Imaging


Beim Magnetic Particle Imaging (MPI) regt ein zeitlich veränderliches Magnetfeld Nanopartikel an, und diese induzieren eine Spannung in Empfangsspulen. Mithilfe einer Systemmatrix kann aus den gemessenen Spannungen die Partikelkonzentration rekonstruiert werden. Die Systemmatrix wird erstellt, indem die Systemantwort auf eine Punktprobe in jedem Voxel gemessen wird. Die Theorie des Compressed Sensing besagt, dass ein Signal unter bestimmten Bedingungen unterabgetastet und verlustfrei rekonstruiert werden kann. Dabei ist es wichtig, dass das Signal eine sparse Repräsentation in einem anderen Raum besitzt und dieser Raum inkohärent zum Akquisitionsraum ist. In diesem Werk wird gezeigt, dass Compressed Sensing bei der Aufnahme von MPI-Systemmatrizen genutzt werden kann. Die Systemmatrix wird unterabgetastet und die Aufnahmezeit reduziert.

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Das bildgebende Verfahren Magnetic Particle Imaging (MPI) ist in der Lage, die räumliche Verteilung eines magnetischen Tracers mit hoher räumlicher und zeitlicher Auflösung darzustellen. Dabei können diese beiden Parameter klassischerweise nicht unabhängig voneinander gesteigert werden

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Das bildgebende Verfahren Magnetic Particle Imaging (MPI) ist in der Lage, die räumliche Verteilung eines magnetischen Tracers mit hoher räumlicher und zeitlicher Auflösung darzustellen. Dabei können diese beiden Parameter klassischerweise nicht unabhängig voneinander gesteigert werden

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8th International Workshop on Magnetic Particle Imaging (IWMPI 2018)


The 8th International Workshop on Magnetic Particle Imaging took place in Hamburg, March 2018. Since the first workshop in 2010, the International Workshop on MPI (IWMPI) has been the premier forum for researchers working in the MPI field. The workshop aims at covering the status and recent developments of both the instrumentation and the tracer material, as they are equally important in designing a well performing MPI system. The main topics presented at the workshop include hardware developments, image reconstruction and systems theory, nanoparticle physics and theory, nanoparticle synthesis, spectroscopy, patient safety, and medical/research applications of MPI: www.iwmpi.org.

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Ksenija Gräfe Bildgebungskonzepte fur Magnetic Particle Imaging


Dieses Buch stellt den weltweit ersten mehrdimensionalen asymmetrischen Magnetic Particle Imaging (MPI) Scanner vor.MPI nutzt zur Bildgebung die nichtlineare Magnetisierungskurve eines superparamagnetischen Tracermaterials. Die Lokalisation dieses Tracermaterials ist mit sehr guter Auflösung und hoher Sensitivität in Echtzeit möglich. Zur Validierung des MPI-Scanners wurden mehrdimensionale Phantome vermessen und rekonstruiert. Zusätzlich wurden Messungen an biologischem Material durchgeführt und Möglichkeiten geschaffen, zukünftig in-vivo-Modelle zu untersuchen. Denkbar ist ein Einsatz dieser innovativen Scannertopologie in der minimal-invasiven Chirurgie durch ein Konzept zur Verkleinerung der Scannergeometrie.Ein medizinisches Anwendungsszenario dieses Scanners liegt in der Lokalisation des Wächterlymphknotens beim Mammakarzinom. In Zukunft könnte so auf die Verwendung von radioaktivem Tracermaterial verzichtet werden.

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Ramesh Venkatesan Magnetic Resonance Imaging. Physical Principles and Sequence Design


New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.

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Manufacturer Wholesale FQ3012 powerful whiteboard magnetic particle absorption diameter 30mm colo

Florian Griese X-Space Reconstruction with Lissajous Trajectories in Magnetic Particle Imaging


Magnetic Particle Imaging (MPI) is a recently introduced medical imaging modality that promises high sensitivity, high resolution and real-time ability by imaging the spatial distribution of super-paramagnetic iron-oxide nanoparticles. The reconstruction techniques can be categorized into frequency and x-space reconstruction. In this book, a comparison between both techniques is made based on a simulation study. The x-space reconstruction technique using the Lissajous trajectories is presented for various parameters of an ideal scanner. Furthermore, the deconvolution process for the x-space reconstruction is performed with two techniques, the Tikhonov and the Wiener deconvolution. Frequency reconstruction and x-space reconstruction are compared in terms of different setups regarding the density of the trajectory, gradient strength and sampling frequency for an ideal scanner and a realistic scanner with classical coil geometry. The advantages and disadvantages of both reconstruction techniques are analyzed in detail.

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Christian Kaethner Elliptical Coils in Magnetic Particle Imaging


Magnetic Particle Imaging is a functional imaging technique used to visualize the distribution of superparamagnetic iron oxide nanoparticles by using magnetic fields. These fields are generated by current carrying coils specifically arranged in different scanner topologies. Up to now, the established geometries of a coil have been either circular shaped or rectangular shaped. The aim of this work is to evaluate the application of approximated elliptical coils. Based on the clinical practice, it is conceivable to integrate a circular single-sided scanner, for example, into a patient table. In order to achieve an optimally adapted result to the medical application, a tradeoff between size, field of view and patient access must be made. The new coil geometry is designed to increase the field of view, without exceeding the width of the patient table and therefore ensure good access to the patient. Besides the integration of this new coil geometry into an existing simulation framework, the simulation is validated by comparing the results to a self-built coil and an already established coil geometry. In addition to this, the application of the coil in different scanner topologies is evaluated.

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Mrignayani Kotecha Magnetic Resonance Imaging in Tissue Engineering


Magnetic Resonance Imaging in Tissue Engineering provides a unique overview of the field of non-invasive MRI assessment of tissue engineering and regenerative medicine Establish a dialogue between the tissue-engineering scientists and imaging experts and serves as a guide for tissue engineers and biomaterial developers alike Provides comprehensive details of magnetic resonance imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs Covers cell-based therapies, engineered cartilage, bone, meniscus, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by MRI Includes a chapter on oxygen imaging method that predominantly is used for assessing hypoxia in solid tumors for improving radiation therapy but has the ability to provide information on design strategies and cellular viability in tissue engineering regenerative medicine

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Patrick Clarysse Multi-modality Cardiac Imaging. Processing and Analysis


The imaging of moving organs such as the heart, in particular, is a real challenge because of its movement. This book presents current and emerging methods developed for the acquisition of images of moving organs in the five main medical imaging modalities: conventional X-rays, computed tomography (CT), magnetic resonance imaging (MRI), nuclear imaging and ultrasound. The availability of dynamic image sequences allows for the qualitative and quantitative assessment of an organ’s dynamics, which is often linked to pathologies.

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Mauricio Castillo Vascular Imaging of the Central Nervous System. Physical Principles, Clinical Applications, and Emerging Techniques


The first book-length reference to thoroughly describe diagnostic and therapeutic advances in the development of vascular radiology over the last decade The last ten years has seen vascular imaging of the central nervous system (CNS) evolve from fairly crude, invasive procedures to more advanced imaging methods that are safer, faster, and more precise—with computed tomographic (CT) and magnetic resonance (MR) imaging methods playing a special role in these advances. Vascular Imaging of the Central Nervous System is the first full-length reference text that shows radiologists—especially neuroradiologists—how to optimize the use of the many techniques available in order to increase the sensitivity and specificity of vascular imaging, thereby improving the diagnosis and treatment of individual patients. Each chapter is formatted carefully and divided into two essential parts: The first part describes the physical principles underlying each imaging technique, along potential associated artifacts and pitfalls; the second part addresses clinical applications and novel applications of each method. With a strong focus on the clinical application of each modality or technique in CNS radiology, this book provides in-depth chapter coverage of: • Ultrasound Vascular Imaging (UVI) • Computed Tomography Angiography (CTA) • Magnetic Resonance Vascular imaging (MRV) • Digital subtraction angiography (DSA) • Brain perfusion techniques: CT and MRI • Plaque imaging • Intravascular imaging • Pediatric vascular imaging Along with numerous illustrations and case studies, Vascular Imaging of the Central Nervous System: Physical Principles, Clinical Applications, and Emerging Techniques is an important book for those faced with choosing from the wide range of choices available for clinical practice.

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Hervé Fanet Medical Imaging Based on Magnetic Fields and Ultrasounds


This book describes the different principles and equipment used in medical imaging. The importance of medical imaging for diagnostics is rapidly increasing. A good working knowledge of all the different possible physical principles involved in medical imaging is now imperative. This book covers many of these principles including matter photon interactions, the principles of detectors, detectors and information processing for radiology, X-ray tomography, positron tomography, single photon tomography and optical tomography.

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Larry Kimberlin Atlas of Clinical Imaging and Anatomy the Equine Head


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